SCHEMBL1345430

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8093412	0.90	GSK3B (0.51)	GSK3BSTAT3HTTTSHRCASP1
	SCHEMBL8100315	0.89	GSK3B (0.52)	GSK3BSTAT3HTTTSHRCASP1
	SCHEMBL8108200	0.89	GSK3B (0.52)	GSK3BSTAT3HTTTSHRCASP1
	SCHEMBL1344459	0.86	GSK3B (0.53)	GSK3B
	SCHEMBL1342789	0.85	STAT3 (0.40)	GSK3BSTAT3HTTTSHRCASP1
	SCHEMBL1186281	0.84	GSK3B (0.51)	GSK3BSTAT3HTTTSHRCASP1
	SCHEMBL1187968	0.83	GSK3B (0.42)	GSK3BSTAT3HTTTSHRCASP1
	SCHEMBL1342484	0.82	STAT3 (0.48)	STAT3HTTTSHRCASP1KDM4E
	SCHEMBL8100207	0.81	GSK3B (0.56)	GSK3BSTAT3HTTTSHRCASP1
	SCHEMBL1187875	0.81	GSK3B (0.48)	GSK3BSTAT3HTTTSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.