Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 12/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222602 | 0.92 | HMGCR (0.49) | HMGCRHDAC1HDAC2HDAC6 | |
| SCHEMBL2222607 | 0.92 | HMGCR (0.49) | HMGCRHDAC1HDAC2HDAC6 | |
| SCHEMBL14243567 | 0.92 | HMGCR (0.45) | HMGCRHDAC1HDAC2HDAC6 | |
| SCHEMBL13453051 | 0.88 | HMGCR (0.48) | HMGCR | |
| SCHEMBL13637171 | 0.86 | HMGCR (0.47) | HMGCRHDAC1HDAC2HDAC6 | |
| SCHEMBL14243679 | 0.86 | HMGCR (0.47) | HMGCR | |
| SCHEMBL13456515 | 0.86 | HMGCR (0.45) | HMGCR | |
| SCHEMBL13637135 | 0.84 | HMGCR (0.46) | HMGCR | |
| SCHEMBL12045143 | 0.80 | HMGCR (0.51) | HMGCRHDAC1HDAC2HDAC6 | |
| SCHEMBL4079319 | 0.79 | HMGCR (0.56) | HMGCRHDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056783-A1 | Novel Process for the Preparation of Statins and their Pharmaceutically Acceptable Salts thereof | MSN LABORATORIES LIMITED (IN) | 2010-03-04 | — | — | US | disclosed |
| WO-2008044243-A9 | NOVEL PROCESS FOR THE PREPARATION OF STATINS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SATYANARAYANA REDDY MANNE (IN) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008044243-A2 | NOVEL PROCESS FOR THE PREPARATION OF STATINS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SATYANARAYANA REDDY MANNE (IN) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056783-A1 | Novel Process for the Preparation of Statins and their Pharmaceutically Acceptable Salts thereof | HMGCR, PCSK9, NPC1L1 | HMGCR 1/4885HDAC1 1089/4885HDAC2 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.