Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 20/20 | 0.61 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.59 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.59 |
| ▸ | TACR2 | P21452 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14241812 | 0.93 | SSTR3 (0.59) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL823850 | 0.93 | SSTR3 (0.59) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL901932 | 0.86 | SSTR3 (0.80) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL9909900 | 0.86 | SSTR3 (0.51) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL13244751 | 0.86 | SSTR3 (0.51) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL13244859 | 0.85 | SSTR3 (0.61) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL9928505 | 0.84 | SSTR3 (0.64) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL13244682 | 0.84 | SSTR3 (0.64) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL23777544 | 0.84 | SSTR3 (0.81) | SSTR3KCNH2SSTR1SSTR5TACR2 | |
| SCHEMBL9928528 | 0.84 | SSTR3 (0.81) | SSTR3KCNH2SSTR1SSTR5TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025553-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-03-11 | — | — | WO | disclosed |