Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226417 | 0.89 | CHRM3 (0.45) | CHRM3 | |
| SCHEMBL1968700 | 0.89 | CHRM3 (0.45) | CHRM3 | |
| SCHEMBL1966327 | 0.82 | CHRM3 (0.44) | CHRM3 | |
| SCHEMBL3230462 | 0.82 | CHRM3 (0.44) | CHRM3 | |
| SCHEMBL1969342 | 0.74 | HDAC1 (0.47) | — | |
| SCHEMBL1969345 | 0.74 | HDAC1 (0.47) | — | |
| SCHEMBL3226412 | 0.73 | BCL9 (0.39) | CHRM3 | |
| SCHEMBL3229853 | 0.73 | HDAC1 (0.44) | CHRM3 | |
| SCHEMBL3229872 | 0.73 | HDAC1 (0.44) | CHRM3 | |
| Iferanserin SCHEMBL658304 | 0.70 | DRD1 (0.62) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031708-A2 | NOVEL ORTHO-AMINOANILIDES FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |