Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213008 | 0.87 | MEN1 (0.36) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL14213014 | 0.83 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL13455534 | 0.83 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL14213009 | 0.81 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL16015507 | 0.81 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL15338277 | 0.81 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL13458326 | 0.79 | MEN1 (0.40) | MEN1KMT2AALDH1A1GAAHTT | |
| SCHEMBL13458184 | 0.76 | MEN1 (0.33) | MEN1KMT2AALDH1A1GAAHTT | |
| SCHEMBL15604496 | 0.76 | MEN1 (0.33) | MEN1KMT2AALDH1A1GAAHTT | |
| SCHEMBL15838346 | 0.72 | MEN1 (0.33) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026124-A1 | PICOLINAMIDE DERIVATIVES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2010-03-11 | — | — | WO | disclosed |