Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 6/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 3/20 | 0.31 |
| ▸ | GSK3B | P49841 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234967 | 0.94 | CCNC (0.37) | CCNCCDK8WNT3AFLT3HDAC3 | |
| SCHEMBL3234953 | 0.94 | CCNC (0.37) | CCNCCDK8WNT3AFLT3HDAC3 | |
| SCHEMBL13458174 | 0.88 | HDAC1 (0.42) | CCNCCDK8HDAC3HDAC1HDAC8 | |
| SCHEMBL10039321 | 0.82 | HDAC1 (0.41) | CCNCCDK8HDAC3HDAC1HDAC8 | |
| SCHEMBL3225727 | 0.81 | CCNC (0.37) | CCNCCDK8FLT3HDAC3HDAC1 | |
| SCHEMBL3225738 | 0.81 | CCNC (0.37) | CCNCCDK8FLT3HDAC3HDAC1 | |
| SCHEMBL3226156 | 0.77 | HDAC1 (0.44) | HDAC3HDAC1KDM1AHDAC2 | |
| SCHEMBL3226196 | 0.77 | HDAC1 (0.44) | HDAC3HDAC1KDM1AHDAC2 | |
| SCHEMBL10039309 | 0.73 | HDAC1 (0.44) | CCNCCDK8HDAC3HDAC1HDAC8 | |
| SCHEMBL13458756 | 0.73 | HDAC1 (0.45) | CCNCCDK8HDAC3HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031708-A2 | NOVEL ORTHO-AMINOANILIDES FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |