Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16522617 | 0.87 | SPHK1 (0.36) | SPHK1 | |
| SCHEMBL14213005 | 0.87 | SPHK1 (0.36) | SPHK1 | |
| SCHEMBL17115522 | 0.85 | SPHK1 (0.36) | SPHK1 | |
| SCHEMBL16526350 | 0.79 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL29359270 | 0.79 | SPHK1 (0.35) | SPHK1 | |
| SCHEMBL12396343 | 0.77 | SPHK1 (0.50) | SPHK1BRD4 | |
| SCHEMBL18878400 | 0.77 | SPHK1 (0.50) | SPHK1BRD4 | |
| SCHEMBL16588188 | 0.76 | SPHK1 (0.38) | SPHK1BRD4 | |
| SCHEMBL16553345 | 0.76 | SPHK1 (0.46) | SPHK1BRD4 | |
| SCHEMBL15336587 | 0.76 | SPHK1 (0.46) | SPHK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026124-A1 | PICOLINAMIDE DERIVATIVES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2010-03-11 | — | — | WO | disclosed |