Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458919 | 0.97 | CCR1 (0.49) | TOP1MAPK1TSHRHSD17B10CCR1 | |
| SCHEMBL16696472 | 0.94 | TOP1 (0.51) | TOP1MAPK1TSHRHSD17B10KDM4E | |
| SCHEMBL17899347 | 0.94 | TOP1 (0.51) | TOP1MAPK1TSHRHSD17B10KDM4E | |
| SCHEMBL13458835 | 0.94 | CCR1 (0.46) | TOP1MAPK1TSHRHSD17B10CCR1 | |
| SCHEMBL16696473 | 0.92 | TOP1 (0.50) | TOP1MAPK1TSHRHSD17B10KDM4E | |
| SCHEMBL13458696 | 0.90 | TOP1 (0.50) | TOP1MAPK1TSHRHSD17B10CCR1 | |
| SCHEMBL3357391 | 0.89 | TOP1 (0.44) | TOP1MAPK1TSHRHSD17B10CCR1 | |
| SCHEMBL22374799 | 0.88 | CCR1 (0.43) | TOP1MAPK1CCR1CCR5CCR8 | |
| SCHEMBL23433999 | 0.87 | MEN1 (0.41) | TOP1MAPK1TSHRHSD17B10CCR1 | |
| SCHEMBL25721773 | 0.87 | TOP1 (0.41) | TOP1MAPK1TSHRHSD17B10CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161272-A1 | Phenanthrolines | BASF SE (DE) | 2010-03-10 | — | — | EP | disclosed |