Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 3/20 | 0.41 |
| ▸ | NR2C2 | P49116 | 3/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936432 | 0.89 | BRAF (0.57) | BRAFLYNMAPK9 | |
| Trifluoroacetic Acid SCHEMBL2670732 | 0.85 | BRAF (0.54) | BRAFLYNMAPK9 | |
| SCHEMBL1935617 | 0.85 | BRAF (0.58) | BRAFLYNMAPK9 | |
| SCHEMBL1935393 | 0.81 | BRAF (0.52) | BRAFS1PR1LYNMAPK9 | |
| SCHEMBL1935509 | 0.80 | BRAF (0.58) | BRAFLYNMAPK9 | |
| SCHEMBL2671441 | 0.78 | BRAF (0.51) | BRAFLYNMAPK9 | |
| SCHEMBL1936713 | 0.78 | BRAF (0.49) | BRAFLYNMAPK9 | |
| SCHEMBL2671039 | 0.76 | BRAF (0.49) | BRAF | |
| SCHEMBL1936594 | 0.76 | BRAF (0.55) | BRAFLYNMAPK9 | |
| SCHEMBL1935989 | 0.76 | BRAF (0.67) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |