Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119001 | 0.92 | BRAF (1.00) | BRAF | |
| SCHEMBL13459655 | 0.90 | BRAF (0.84) | BRAF | |
| SCHEMBL13459658 | 0.88 | BRAF (0.84) | BRAF | |
| SCHEMBL13459377 | 0.86 | BRAF (0.79) | BRAF | |
| SCHEMBL13459129 | 0.86 | BRAF (0.82) | BRAF | |
| SCHEMBL13459660 | 0.86 | BRAF (0.84) | BRAF | |
| SCHEMBL10119194 | 0.85 | BRAF (0.83) | BRAF | |
| SCHEMBL10119155 | 0.83 | BRAF (0.84) | BRAF | |
| SCHEMBL10119201 | 0.83 | BRAF (0.84) | BRAF | |
| SCHEMBL10118975 | 0.82 | BRAF (1.00) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010026262-A1 | PYRIDO [5, 4-D] PYRIMIDINES AS CELL PROLIFERATION INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |