Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.52 |
| ▸ | PPARA | Q07869 | 10/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460768 | 0.86 | PPARD (0.61) | PPARDPPARAPPARG | |
| SCHEMBL3418765 | 0.85 | PPARD (0.69) | PPARDPPARATP53LMNAHPGD | |
| SCHEMBL13460943 | 0.85 | PPARD (0.49) | PPARDPPARALMNAHPGDPPARG | |
| SCHEMBL13460939 | 0.84 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL13460846 | 0.84 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL13460798 | 0.83 | PPARD (0.71) | PPARDPPARAPPARG | |
| SCHEMBL13460889 | 0.81 | HPGD (0.47) | PPARALMNAHPGDPPARG | |
| SCHEMBL13460759 | 0.81 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL13460799 | 0.81 | PPARD (0.53) | PPARDPPARALMNAPPARG | |
| SCHEMBL13460749 | 0.79 | PPARD (0.54) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |