Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460774 | 0.90 | PPARD (0.45) | PPARDPPARAERN1TP53NPC1 | |
| SCHEMBL13460770 | 0.88 | HDAC1 (0.45) | PPARDPPARAERN1TP53MAPT | |
| SCHEMBL3414175 | 0.88 | PPARD (0.54) | PPARDPPARATP53LMNAMAPT | |
| SCHEMBL13460753 | 0.86 | PPARD (0.41) | PPARDPPARATP53LMNAMAPT | |
| SCHEMBL13460775 | 0.84 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL13461039 | 0.83 | ERN1 (0.45) | PPARDPPARAERN1LMNAMAPT | |
| SCHEMBL13461040 | 0.82 | ERN1 (0.42) | PPARDPPARAERN1MAPTHTT | |
| SCHEMBL3414385 | 0.82 | PPARD (0.55) | PPARDPPARATP53LMNANPC1 | |
| SCHEMBL13460858 | 0.81 | PPARD (0.51) | PPARDPPARATP53CYP1A2RECQL | |
| SCHEMBL3416948 | 0.81 | PPARD (0.59) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |