Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.74 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460872 | 0.90 | FFAR1 (0.68) | FFAR1FFAR4AKR1B1PTGER4NR1H2 | |
| SCHEMBL1756354 | 0.88 | MAOB (0.60) | FFAR1FFAR4RXRAMAOBPPARD | |
| SCHEMBL23296113 | 0.86 | GRIN2D (0.57) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL15297882 | 0.85 | MAOB (0.63) | FFAR1MAOBPPARGPPARD | |
| SCHEMBL3575842 | 0.83 | FFAR1 (0.55) | FFAR1FFAR4AKR1B1ANO1PTGER4 | |
| SCHEMBL4448605 | 0.83 | FFAR1 (0.61) | FFAR1FFAR4AKR1B1PTGER4PTGER3 | |
| SCHEMBL13460871 | 0.82 | FFAR1 (0.60) | FFAR1FFAR4AKR1B1MAOB | |
| SCHEMBL13460991 | 0.82 | PTGER4 (0.60) | FFAR1FFAR4AKR1B1PTGER4PTGER3 | |
| SCHEMBL3418553 | 0.82 | FFAR1 (0.55) | FFAR1FFAR4AKR1B1ANO1NR1H2 | |
| SCHEMBL13460836 | 0.82 | MRGPRX4 (0.61) | FFAR1FFAR4PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |