Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455637 | 0.81 | MYC (0.42) | MYCXDHABCG2ALDH1A1NPY5R | |
| SCHEMBL17116812 | 0.81 | MYC (0.54) | MYCXDHABCG2USP30NPY5R | |
| SCHEMBL14875772 | 0.80 | CDK8 (0.48) | CA12CA1CA2CA9TRIM24 | |
| SCHEMBL28166485 | 0.80 | MYC (0.41) | MYCXDHABCG2ALDH1A1NPY5R | |
| SCHEMBL9792895 | 0.79 | MYC (0.62) | MYCXDHABCG2USP30NPY5R | |
| SCHEMBL31133396 | 0.79 | MYC (0.62) | MYCXDHABCG2USP30NPY5R | |
| SCHEMBL16180216 | 0.79 | CDK8 (0.44) | CA12CA1CA2CA9TRIM24 | |
| SCHEMBL31090305 | 0.78 | MYC (0.58) | MYCXDHABCG2ALDH1A1NPY5R | |
| SCHEMBL317097 | 0.78 | MYC (0.58) | MYCXDHABCG2ALDH1A1NPY5R | |
| SCHEMBL9792841 | 0.77 | CLK4 (0.61) | MYCCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |