Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | SDHA | P31040 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CALML3 | P27482 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 10/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578023 | 1.00 | MAOB (0.55) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL3570260 | 0.94 | MAOB (0.63) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL3570262 | 0.94 | MAOB (0.63) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL13349091 | 0.92 | MAOB (0.56) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL3571136 | 0.92 | MAOB (0.56) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL3582145 | 0.90 | MAOB (0.55) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL3582151 | 0.90 | MAOB (0.55) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL3573373 | 0.90 | MAOB (0.52) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL15721442 | 0.90 | MAOB (0.52) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL13349046 | 0.90 | MAOB (0.52) | MAOBMAOAPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729269-B2 | Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy | WOCKHARDT LIMITED (IN) | 2014-05-20 | — | — | US | disclosed |
| US-7687627-B2 | Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy | WOCKHARDT LIMITED (IN) | 2010-03-30 | — | — | US | disclosed |