Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.56 |
| ▸ | PDE4A | P27815 | 12/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489126 | 0.96 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463550 | 0.91 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463554 | 0.90 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463549 | 0.90 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463547 | 0.89 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463555 | 0.89 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463556 | 0.89 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL12489698 | 0.89 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463552 | 0.88 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13463548 | 0.88 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2013-10-31 | — | — | US | disclosed |
| US-8470803-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| WO-2010027975-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | NFKBIA, BCL6B, TNF | PDE4B 543/4885PDE4A 878/4885PDE4C 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.