Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 12/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86345 | 0.90 | S1PR1 (0.64) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL86262 | 0.89 | S1PR1 (0.66) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| Hydrochloric Acid SCHEMBL79486 | 0.89 | S1PR1 (0.63) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| Hydrochloric Acid SCHEMBL78811 | 0.88 | S1PR1 (0.65) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL86388 | 0.88 | S1PR1 (0.67) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL86526 | 0.87 | S1PR1 (0.72) | S1PR1S1PR3USP28USP25TNNC1 | |
| Hydrochloric Acid SCHEMBL82222 | 0.87 | S1PR1 (0.66) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL86212 | 0.87 | S1PR1 (0.66) | S1PR1S1PR3USP28USP25TNNC1 | |
| Hydrochloric Acid SCHEMBL81226 | 0.86 | S1PR1 (0.71) | S1PR1S1PR3USP28USP25TNNC1 | |
| SCHEMBL86301 | 0.86 | S1PR1 (0.71) | S1PR1S1PR3TNNC1SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168944-B1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-11 | — | — | EP | disclosed |
| EP-2168944-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |