Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29235946 | 0.86 | TSHR (0.68) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL7937771 | 0.84 | MGAM (0.55) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL8657754 | 0.83 | TSHR (0.62) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL23309344 | 0.81 | TSHR (0.59) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL13209024 | 0.81 | TSHR (0.46) | TSHRLMNAKDM4EMGAMGAA | |
| Dimethyl Succinate SCHEMBL28185979 | 0.81 | TSHR (0.87) | TSHRLMNAKDM4EMGAMGAA | |
| Dimethyl Succinate SCHEMBL9392460 | 0.81 | TSHR (0.87) | TSHRLMNAKDM4EMGAMGAA | |
| Dimethyl Succinate SCHEMBL10213 | 0.81 | TSHR (1.00) | TSHRLMNAKDM4EMGAMGAA | |
| Dimethyl Succinate SCHEMBL28054469 | 0.81 | TSHR (1.00) | TSHRLMNAKDM4EMGAMGAA | |
| SCHEMBL13227448 | 0.79 | TSHR (0.56) | TSHRLMNAKDM4EMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282853-A1 | PROCESS FOR THE PREPARATION OF MESACONIC ACID ESTERS | Symrise AG (DE) | 2023-11-29 | — | — | EP | disclosed |
| WO-2007017522-A9 | FERROCENE-DIPHOSPHINE LIGANDS | SOLVIAS AG (CH) | 2008-02-07 | — | — | WO | disclosed |
| WO-2007017522-A1 | FERROCENE-DIPHOSPHINE LIGANDS | SOLVIAS AG (CH) | 2007-02-15 | — | — | WO | disclosed |