Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18829853 | 0.93 | EZH2 (0.71) | EZH2 | |
| SCHEMBL15731220 | 0.92 | EZH2 (0.84) | EZH2 | |
| SCHEMBL15710378 | 0.92 | EZH2 (0.84) | EZH2 | |
| SCHEMBL18829782 | 0.91 | EZH2 (0.69) | EZH2 | |
| SCHEMBL18829876 | 0.91 | EZH2 (0.71) | EZH2 | |
| SCHEMBL13468501 | 0.90 | EZH2 (0.66) | EZH2 | |
| SCHEMBL13467967 | 0.86 | EZH2 (0.84) | EZH2 | |
| SCHEMBL15709941 | 0.86 | EZH2 (0.84) | EZH2 | |
| SCHEMBL15710233 | 0.85 | EZH2 (0.83) | EZH2 | |
| SCHEMBL13468502 | 0.85 | EZH2 (0.83) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470396-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-3165520-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme Inc (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2012142513-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2012-10-18 | — | — | WO | disclosed |