Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13194258 | 0.91 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL13194253 | 0.91 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL13194233 | 0.88 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL13194403 | 0.88 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL17758706 | 0.85 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL13194402 | 0.84 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL17169317 | 0.84 | BACE1 (0.68) | BACE1BACE2 | |
| SCHEMBL17119116 | 0.83 | BACE1 (0.84) | BACE1BACE2 | |
| SCHEMBL13194254 | 0.83 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL13193629 | 0.82 | BACE1 (1.00) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012139993-A1 | 1,3 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-10-18 | — | — | WO | disclosed |