Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 1.00 |
| ▸ | TOP2A | P11388 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | NT5E | P21589 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 1/20 | 1.00 |
| ▸ | CES2 | O00748 | 2/20 | 0.74 |
| ▸ | CES1 | P23141 | 2/20 | 0.74 |
| ▸ | RORC | P51449 | 4/20 | 0.70 |
| ▸ | ALB | P02768 | 3/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | GLI1 | P08151 | 1/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.70 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.70 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.70 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.70 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betulin SCHEMBL14397735 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL8223535 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL17749655 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL19452465 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL13098066 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL14144235 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL14339169 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL14368529 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL20776118 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A | |
| Betulin SCHEMBL14144210 | 1.00 | PTPN1 (1.00) | PTPN1TOP2AUSP2LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142141-A1 | SYNTHESIS AND USE OF GLYCOSIDE PRO-DRUG ANALOGS | NuTek Pharma Ltd. (US) | 2012-10-18 | — | — | WO | disclosed |