Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 2/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12743486 | 0.92 | GLP1R (0.49) | GLP1RSIRT5ALBTLR2CCKAR | |
| SCHEMBL12147613 | 0.92 | GLP1R (0.47) | GLP1RSIRT5ALBTLR2CCKAR | |
| SCHEMBL12767745 | 0.92 | GLP1R (0.51) | GLP1RSIRT5ALBTLR2ESR1 | |
| SCHEMBL12972408 | 0.92 | GLP1R (0.49) | GLP1RSIRT5ALBTLR2CCKAR | |
| SCHEMBL13475034 | 0.90 | GLP1R (0.56) | GLP1RSIRT5ALBTLR2CCKAR | |
| SCHEMBL12147610 | 0.89 | GLP1R (0.45) | GLP1RSIRT5ALBTLR2ESR1 | |
| SCHEMBL12147600 | 0.87 | GLP1R (0.48) | GLP1RALB | |
| SCHEMBL12064338 | 0.87 | GLP1R (0.41) | GLP1RSIRT5ALBFOLH1ADRA1A | |
| SCHEMBL14422365 | 0.85 | GLP1R (0.42) | GLP1RALBTLR2CCKARCCKBR | |
| SCHEMBL16350406 | 0.85 | GLP1R (0.46) | GLP1RALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666979-B2 | polyvalent targeting ligands that bind to cells used for diagnosis of diseases sensitivity to angiogenesis factor | BRACCO INTERNATIONAL B.V. (NL) | 2010-02-23 | — | — | US | disclosed |