Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930852 | 1.00 | CHKA (0.59) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL13475883 | 1.00 | CHKA (0.59) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL13475879 | 0.97 | CHKA (0.56) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL13475882 | 0.93 | MAPT (0.53) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL13475878 | 0.91 | NPC1 (0.54) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL13475885 | 0.91 | CHKA (0.51) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL13475884 | 0.90 | CHKA (0.59) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL9999731 | 0.90 | NPC1 (0.58) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13475871 | 0.90 | NPC1 (0.58) | CHKANPC1LMNANFKB1NFKB2 | |
| SCHEMBL13475862 | 0.90 | NPC1 (0.58) | CHKANPC1LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7658864-B2 | Liquid crystal composition, optical compensation film and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20090040435-A1 | LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-02-12 | — | — | US | disclosed |
| US-20090009693-A1 | Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device | FUJIFILM CORPORATION (JP) | 2009-01-08 | — | — | US | disclosed |