SCHEMBL13476451

SCHEMBL13476451

CS(=O)(=O)NC(c1ccc(Cl)c(Cl)c1)C1CCNCC1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 17/20 0.60
SLC6A4 P31645 17/20 0.60
SLC6A3 Q01959 17/20 0.60
AKT1 P31749 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13476459 0.87 SLC6A2 (0.58) SLC6A2SLC6A4SLC6A3AKT1
SCHEMBL13476461 0.84 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3AKT1
SCHEMBL23216214 0.78 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3AKT1
SCHEMBL29745352 0.78 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3AKT1
SCHEMBL13476422 0.75 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3AKT1
SCHEMBL13476496 0.74 SLC6A2 (1.00) SLC6A2SLC6A4SLC6A3
SCHEMBL13476460 0.73 SLC6A2 (0.66) SLC6A2SLC6A4SLC6A3
SCHEMBL13476424 0.73 CCR8 (0.42) SLC6A2SLC6A4SLC6A3
SCHEMBL7414296 0.73 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3AKT1
SCHEMBL13476418 0.72 SLC6A2 (0.57) SLC6A2SLC6A4SLC6A3AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010016554-A1 CYCLIC AMINE COMPOUND 武田薬品工業株式会社 (JP) 2010-02-11 WO disclosed