Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.52 |
| ▸ | TXK | P42681 | 1/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1550203 | 0.87 | SYK (0.50) | SYKTXKKARS1SLK | |
| SCHEMBL16520293 | 0.87 | SYK (0.50) | SYKTXKKARS1SLK | |
| SCHEMBL1550408 | 0.87 | SYK (0.50) | SYKTXKKARS1SLK | |
| SCHEMBL1549984 | 0.85 | SYK (0.51) | SYK | |
| SCHEMBL1550464 | 0.84 | SYK (0.43) | SYKTXKKARS1SLK | |
| SCHEMBL16520292 | 0.84 | SYK (0.47) | SYKTXKKARS1SLK | |
| SCHEMBL1550178 | 0.83 | SYK (0.52) | SYKTXKKARS1SLK | |
| SCHEMBL12235404 | 0.80 | SYK (0.46) | SYK | |
| SCHEMBL12235403 | 0.80 | SYK (0.46) | SYK | |
| SCHEMBL12235371 | 0.77 | SYK (0.44) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313406-B1 | 4-DIMETHYLAMINOPHENYL SUBSTITUTED NAPTHTHYRIDINES UND THEIR USE AS MEDICINE | BOEHRINGER INGELHEIM INT (DE) | 2015-02-25 | — | — | EP | disclosed |
| WO-2010015518-A2 | 4-DIMETHYLAMINO-PHENYL-SUBSTITUTED NAPHTHYRIDINES, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNTIONAL GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |