SCHEMBL13478761

SCHEMBL13478761

Bc1cc2c3c(n(Cc4cccc(F)c4)c2cc1F)CCC(NC(=O)C(C)C)C3

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 9/20 0.44
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.38
SIGMAR1 Q99720 3/20 0.37
KCNH2 Q12809 1/20 0.35
MCHR1 Q99705 1/20 0.35
TBXA2R P21731 1/20 0.35
PTGDR Q13258 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
UBE2N P61088 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1874282 0.91 PTGDR2 (0.44) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL14624668 0.91 PTGDR2 (0.44) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL1878914 0.90 PTGDR2 (0.43) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL14624562 0.90 PTGDR2 (0.46) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL1882590 0.87 PTGDR2 (0.46) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL1871468 0.87 PTGDR2 (0.49) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL1877449 0.86 PTGDR2 (0.50) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL12637031 0.86 PTGDR2 (0.48) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL1877855 0.86 PTGDR2 (0.48) PTGDR2MTNR1AMTNR1BFABP3FABP4
SCHEMBL14624661 0.86 PTGDR2 (0.43) PTGDR2MTNR1AMTNR1BFABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902026-B1 TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) LILLY CO ELI (US) 2010-02-17 EP disclosed