Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146447 | 1.00 | KCNH2 (0.65) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4554687 | 0.99 | KCNH2 (0.64) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3223894 | 0.99 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL3225935 | 0.95 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL3232107 | 0.95 | KCNH2 (0.58) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3230694 | 0.94 | KCNH2 (0.57) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3224663 | 0.94 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL3154009 | 0.93 | KCNH2 (0.59) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3217963 | 0.92 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL3149659 | 0.91 | KCNH2 (0.53) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954697-B1 | PERI CONDENSED TRICYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2010-02-24 | — | — | EP | disclosed |