Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 6/20 | 0.32 |
| ▸ | BACE1 | P56817 | 4/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26962703 | 0.77 | GAA (0.38) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL29270790 | 0.77 | GAA (0.38) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL14387586 | 0.76 | GAA (0.39) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL26962099 | 0.76 | GAA (0.44) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL24076694 | 0.75 | GAA (0.43) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL29270785 | 0.75 | GAA (0.43) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL26961952 | 0.74 | GAA (0.41) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL29270789 | 0.74 | GAA (0.43) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL29270699 | 0.73 | GAA (0.40) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL30675678 | 0.73 | GAA (0.40) | GAAEPHX2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029596-B1 | 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZOTHIAZEPINES, THE PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME | SANOFI AVENTIS (FR) | 2010-02-24 | — | — | EP | disclosed |