Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 16/20 | 0.55 |
| ▸ | CCR6 | P51684 | 4/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.43 |
| ▸ | CCR7 | P32248 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479627 | 0.88 | CXCR2 (0.52) | CXCR2CCR6CXCR1 | |
| SCHEMBL13479527 | 0.88 | CXCR2 (0.52) | CXCR2CCR6CXCR1 | |
| SCHEMBL13479682 | 0.88 | CXCR2 (0.52) | CXCR2CCR6CXCR1CCR7 | |
| SCHEMBL13479554 | 0.87 | CXCR2 (0.69) | CXCR2CCR6CXCR1CCR7 | |
| SCHEMBL14450836 | 0.86 | CXCR2 (0.53) | CXCR2CCR6CXCR1 | |
| SCHEMBL14450207 | 0.86 | CXCR2 (0.50) | CXCR2CCR6CXCR1 | |
| SCHEMBL14450744 | 0.82 | CXCR2 (0.47) | CXCR2CCR6CXCR1 | |
| SCHEMBL12263178 | 0.82 | CXCR2 (0.78) | CXCR2CCR6CXCR1 | |
| SCHEMBL12262421 | 0.82 | CXCR2 (0.78) | CXCR2CCR6CXCR1 | |
| SCHEMBL12263167 | 0.80 | CXCR2 (0.74) | CXCR2CCR6CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1818325-B1 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORP (US) | 2010-02-24 | — | — | EP | disclosed |