Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | GSK3B | P49841 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196197 | 0.87 | EPHX1 (1.00) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL10089308 | 0.84 | EPHX1 (0.83) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL7742908 | 0.84 | EPHX1 (0.68) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL30393282 | 0.84 | KDM4E (0.82) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL1276481 | 0.84 | KDM4E (0.82) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL14424459 | 0.83 | EPHX1 (0.81) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL22168472 | 0.83 | EPHX1 (0.67) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL13044587 | 0.82 | EPHX1 (0.66) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL29971510 | 0.82 | KDM4E (1.00) | EPHX1KDM4EGSK3BKMT2AMEN1 | |
| SCHEMBL1395176 | 0.82 | KDM4E (1.00) | EPHX1KDM4EGSK3BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163808-A1 | COMPOUND OR SALT THEREOF, NATURAL KILLER T CELL ACTIVATOR, AND PHARMACEUTICAL COMPOSITION | 学校法人慶應義塾 | 2017-09-28 | — | — | WO | disclosed |
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | disclosed |