Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 17/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966655 | 1.00 | EPHX1 (0.72) | EPHX1KDM4EALDH1A1EPHX2NPC1 | |
| SCHEMBL13480574 | 1.00 | EPHX1 (0.72) | EPHX1KDM4EALDH1A1EPHX2NPC1 | |
| SCHEMBL965080 | 0.98 | EPHX1 (0.69) | EPHX1KDM4EALDH1A1EPHX2NPC1 | |
| SCHEMBL968340 | 0.94 | EPHX1 (0.63) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL965926 | 0.89 | — | — | |
| SCHEMBL15263332 | 0.89 | EPHX1 (0.57) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL6357682 | 0.84 | EPHX1 (1.00) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL12196028 | 0.84 | EPHX1 (1.00) | EPHX1KDM4EALDH1A1EPHX2 | |
| SCHEMBL13062891 | 0.82 | SMN1; SMN2 (0.68) | EPHX1KDM4EALDH1A1EPHX2NPC1 | |
| SCHEMBL2751260 | 0.82 | EPHX1 (0.96) | EPHX1KDM4EALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | disclosed |