Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414971 | 1.00 | AR (0.52) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL13870693 | 1.00 | AR (0.52) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL4414982 | 1.00 | AR (0.52) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL7172600 | 1.00 | AR (0.52) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL5736189 | 0.84 | AR (0.56) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL13480901 | 0.84 | AR (0.56) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL3181519 | 0.84 | AR (0.56) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL3181530 | 0.84 | AR (0.56) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL3187283 | 0.84 | AR (0.56) | ARCTSBALDH1A1TDP1GAA | |
| SCHEMBL13989370 | 0.83 | AR (0.48) | ARCTSBALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655689-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |