Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | USP2 | O75604 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 5/20 | 0.49 |
| ▸ | CASP7 | P55210 | 5/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.49 |
| ▸ | HBB | P68871 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29456891 | 0.85 | SLC16A3 (0.66) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL2844010 | 0.85 | SLC16A3 (0.66) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL13486919 | 0.84 | SLC16A3 (0.61) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL3206016 | 0.83 | SLC16A3 (0.64) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL3208096 | 0.82 | SLC16A3 (0.59) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL2576387 | 0.81 | SLC16A3 (0.66) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL13050804 | 0.79 | SLC16A3 (0.70) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL26307693 | 0.79 | SLC16A3 (0.63) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL28109948 | 0.78 | SLC16A3 (0.73) | SLC16A3KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL13486876 | 0.78 | SLC16A3 (0.69) | SLC16A3KMT2AMEN1ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048604-A1 | Ligands for Aldoketoreductases | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2010-02-25 | — | — | US | disclosed |
| US-20100048604-A1 | Ligands for Aldoketoreductases | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048604-A1 | Ligands for Aldoketoreductases | AKR1C2, AKR1C1, AKR1B1 | SLC16A3 802/4885KMT2A 3808/4885MEN1 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.