Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19440077 | 0.86 | HSD17B10 (0.47) | HSD17B10TDP1SPHK1USP2HTT | |
| SCHEMBL16248045 | 0.83 | HSD17B10 (0.52) | HSD17B10TDP1SPHK1USP2HTT | |
| SCHEMBL17955759 | 0.83 | HSD17B10 (0.44) | HSD17B10TDP1SPHK1USP2 | |
| SCHEMBL460836 | 0.82 | USP2 (0.32) | USP2HTT | |
| SCHEMBL133719 | 0.81 | TDP1 (0.53) | HSD17B10TDP1 | |
| SCHEMBL133724 | 0.81 | HSD17B10 (0.36) | HSD17B10 | |
| SCHEMBL12927830 | 0.81 | USP2 (0.42) | HSD17B10TDP1SPHK1USP2HTT | |
| SCHEMBL9715030 | 0.81 | USP2 (0.55) | HSD17B10USP2HTT | |
| SCHEMBL9065049 | 0.81 | HSD17B10 (0.45) | HSD17B10TDP1SPHK1USP2HTT | |
| SCHEMBL16248046 | 0.80 | HSD17B10 (0.41) | HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742053-B2 | Polyamide-polysiloxane compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2014-06-03 | — | — | US | disclosed |
| US-20100044615-A1 | Novel Polyamide-Polysiloxane Compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044615-A1 | Novel Polyamide-Polysiloxane Compounds | PUF60, MUS81, PARG | HSD17B10 3934/4885TDP1 1967/4885SPHK1 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.