SCHEMBL13488176

SCHEMBL13488176

CN1c2ccccc2N(C)c2cc(-c3c4ccccc4c(-c4ccc5c(c4)C(C)(C)c4ccccc4-5)c4cc(-c5ccc6c(c5)C(C)(C)c5ccccc5-6)ccc34)ccc21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.34
PDK2 Q15119 9/20 0.33
PGR P06401 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13487943 0.98 PDK2 (0.37) CHEK1PDK2PGR
SCHEMBL13487796 0.97 CHEK1 (0.33) CHEK1PDK2
SCHEMBL13487408 0.94 PDK2 (0.32) CHEK1PDK2PGR
SCHEMBL13488095 0.94 AKT1 (0.40) CHEK1PDK2KDM4EMEN1MAPT
SCHEMBL13487867 0.92 PDK2 (0.36) CHEK1PDK2PGRKDM4EMAPT
SCHEMBL13488316 0.92 PDK2 (0.36) CHEK1PDK2PGRKDM4EMAPT
SCHEMBL13488174 0.92 CHEK1 (0.34) CHEK1PDK2KDM4EMEN1MAPT
SCHEMBL13488021 0.91 MEN1 (0.36) KDM4EMEN1MAPTMAPK1KMT2A
SCHEMBL13487939 0.91 PDK2 (0.36) CHEK1PDK2KDM4EMEN1MAPT
SCHEMBL13487576 0.91 PDK2 (0.32) CHEK1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 CHEK1 4787/4885PDK2 1456/4885PGR 4215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.