Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.78 |
| ▸ | NR1H3 | Q13133 | 13/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1092735 | 0.88 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL13492015 | 0.85 | NR1H2 (0.58) | NR1H2NR1H3CYP3A4CYP2C19 | |
| SCHEMBL1104495 | 0.85 | NR1H2 (0.66) | NR1H2NR1H3 | |
| SCHEMBL13601619 | 0.84 | NR1H2 (0.88) | NR1H2NR1H3 | |
| SCHEMBL1092542 | 0.83 | NR1H2 (0.75) | NR1H2NR1H3 | |
| SCHEMBL1092805 | 0.83 | NR1H2 (0.61) | NR1H2NR1H3 | |
| SCHEMBL1104494 | 0.81 | NR1H2 (0.61) | NR1H2NR1H3 | |
| SCHEMBL1093156 | 0.80 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL1104496 | 0.80 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL1104500 | 0.80 | NR1H2 (1.00) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048610-A1 | CARBINOL DERIVATIVES HAVING CYCLIC LINKER | KOWA COMPANY, LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20100048610-A1 | CARBINOL DERIVATIVES HAVING CYCLIC LINKER | KOWA COMPANY, LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048610-A1 | CARBINOL DERIVATIVES HAVING CYCLIC LINKER | NR1H2, NR1H3, LDLR | NR1H2 1/4885NR1H3 2/4885CYP3A4 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.