Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.34 |
| ▸ | MTOR | P42345 | 8/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13492725 | 0.91 | ACACB (0.37) | ACACBPIK3CAMTORIRAK4 | |
| SCHEMBL13492715 | 0.89 | ACACB (0.35) | ACACBPIK3CAMTORIRAK4 | |
| SCHEMBL10093929 | 0.86 | IRAK4 (0.47) | ACACBIRAK4 | |
| SCHEMBL13492731 | 0.86 | IRAK4 (0.47) | ACACBIRAK4 | |
| SCHEMBL13492703 | 0.86 | ACACB (0.34) | ACACBPIK3CAMTOR | |
| SCHEMBL13492767 | 0.79 | ACACB (0.34) | ACACB | |
| SCHEMBL13492722 | 0.79 | IRAK4 (0.35) | ACACBPIK3CAMTORIRAK4 | |
| SCHEMBL13492707 | 0.78 | MTOR (0.35) | ACACBPIK3CAMTORIRAK4 | |
| SCHEMBL13492727 | 0.78 | PIK3CA (0.35) | ACACBPIK3CAMTORIRAK4 | |
| SCHEMBL13492738 | 0.78 | IRAK4 (0.36) | PIK3CAMTORIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022125-A1 | ETHYNYL-SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |