Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 19/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058198 | 0.87 | IRAK4 (0.56) | IRAK4DYRK1A | |
| SCHEMBL12057726 | 0.85 | IRAK4 (0.53) | IRAK4DYRK1A | |
| SCHEMBL12057991 | 0.84 | IRAK4 (0.44) | IRAK4DYRK1A | |
| SCHEMBL12057855 | 0.83 | IRAK4 (0.46) | IRAK4DYRK1A | |
| SCHEMBL12058448 | 0.82 | IRAK4 (0.46) | IRAK4DYRK1A | |
| SCHEMBL12037106 | 0.82 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL12057992 | 0.82 | IRAK4 (0.45) | IRAK4DYRK1A | |
| SCHEMBL12057851 | 0.82 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL12058457 | 0.82 | IRAK4 (0.45) | IRAK4DYRK1A | |
| SCHEMBL12057740 | 0.81 | IRAK4 (0.46) | IRAK4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |