Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12057865 | 0.90 | IRAK4 (0.34) | IRAK4KDM4ERECQLATM | |
| SCHEMBL13493510 | 0.90 | IRAK4 (0.34) | IRAK4KDM4ERECQLATM | |
| SCHEMBL12058474 | 0.88 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL12037051 | 0.88 | IRAK4 (0.50) | IRAK4 | |
| SCHEMBL12057712 | 0.81 | IRAK4 (0.34) | IRAK4KDM4ERECQLATM | |
| SCHEMBL12038710 | 0.79 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL12058173 | 0.78 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL12038730 | 0.77 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL12058160 | 0.77 | CCNA2 (0.31) | KDM4ERECQLATM | |
| SCHEMBL12038597 | 0.76 | IRAK4 (0.53) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |