Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036803 | 0.90 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL12057718 | 0.82 | JAK2 (0.38) | IRAK4JAK2TYK2 | |
| SCHEMBL12037812 | 0.80 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL13493372 | 0.79 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL12058480 | 0.79 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL12037840 | 0.77 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL12058332 | 0.77 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL13493530 | 0.76 | IRAK4 (0.52) | IRAK4 | |
| SCHEMBL12058483 | 0.75 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL13493690 | 0.75 | IRAK4 (0.40) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |