Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | DNM2 | P50570 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058277 | 0.92 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL12038189 | 0.88 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL12057797 | 0.86 | MERTK (0.34) | FLT3TYRO3MERTKGAS6 | |
| SCHEMBL12058390 | 0.84 | IRAK4 (0.38) | IRAK4 | |
| SCHEMBL12058523 | 0.83 | — | — | |
| SCHEMBL12038191 | 0.81 | IRAK4 (0.50) | IRAK4 | |
| SCHEMBL12057775 | 0.81 | IRAK4 (0.36) | IRAK4FLT3TYRO3MERTKGAS6 | |
| SCHEMBL12038175 | 0.80 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL12038198 | 0.79 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL13493734 | 0.79 | IRAK4 (0.33) | IRAK4FLT3TYRO3MERTKGAS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |