Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | F12 | P00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058479 | 0.90 | IRAK4 (0.39) | IRAK4PLAUMAOBCHRM2CHRM4 | |
| SCHEMBL13493506 | 0.87 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL12058262 | 0.87 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL13493672 | 0.86 | IRAK4 (0.37) | IRAK4 | |
| SCHEMBL13493495 | 0.84 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL12036736 | 0.84 | IRAK4 (0.56) | IRAK4 | |
| SCHEMBL13493437 | 0.83 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL12058362 | 0.82 | IRAK4 (0.41) | IRAK4 | |
| SCHEMBL13493429 | 0.80 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL13493443 | 0.79 | IRAK4 (0.35) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |