Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 18/20 | 0.63 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.43 |
| ▸ | MERTK | Q12866 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12057847 | 0.97 | IRAK4 (0.61) | IRAK4TYRO3MERTKFLT3GAS6 | |
| SCHEMBL12058493 | 0.97 | IRAK4 (0.61) | IRAK4TYRO3MERTKFLT3GAS6 | |
| SCHEMBL21105746 | 0.95 | IRAK4 (0.70) | IRAK4 | |
| SCHEMBL12058437 | 0.92 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL12057815 | 0.91 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL12058046 | 0.90 | IRAK4 (0.59) | IRAK4 | |
| SCHEMBL12058018 | 0.89 | IRAK4 (0.67) | IRAK4 | |
| SCHEMBL12058215 | 0.89 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL12057683 | 0.87 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL13493527 | 0.87 | IRAK4 (0.57) | IRAK4TYRO3MERTKFLT3GAS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |