Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.50 |
| ▸ | GRM5 | P41594 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13494214 | 0.83 | DPP4 (0.49) | TLR9TLR8TLR7GRM5NPC1 | |
| SCHEMBL13494244 | 0.81 | GRM5 (0.53) | TLR8TLR7GRM5NPC1RAB9A | |
| SCHEMBL2697700 | 0.80 | GRM5 (0.45) | TLR9TLR8TLR7GRM5NPC1 | |
| SCHEMBL18374878 | 0.78 | GRM5 (0.43) | GRM5NPC1RAB9A | |
| SCHEMBL21845385 | 0.77 | GRM5 (0.45) | TLR9TLR8TLR7GRM5NPC1 | |
| SCHEMBL13494203 | 0.75 | GRM5 (0.41) | GRM5NPC1RAB9AP2RX3 | |
| SCHEMBL1106412 | 0.73 | GRM5 (0.48) | GRM5NPC1RAB9AKDM4E | |
| SCHEMBL22966519 | 0.73 | RAD52 (0.43) | TLR9TLR8TLR7GRM5NPC1 | |
| SCHEMBL22966517 | 0.72 | RAD52 (0.45) | TLR9TLR8TLR7GRM5NPC1 | |
| SCHEMBL15490041 | 0.70 | DPP8 (0.57) | TLR9TLR8TLR7GRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014611-A1 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE HISTONE DEACETYLASE INHIBITOR COMPOUNDS | GILEAD COLORADO, INC. (US) | 2010-02-04 | — | — | WO | disclosed |