SCHEMBL13495347

SCHEMBL13495347

COc1ccc2cccc3c2c1C(=O)N(OC)C3=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
KDM4E B2RXH2 7/20 0.47
GAA P10253 1/20 0.47
RECQL P46063 1/20 0.47
PRMT1 Q99873 1/20 0.46
TDP1 Q9NUW8 3/20 0.45
ALDH1A1 P00352 7/20 0.45
PKM P14618 1/20 0.45
MAPT P10636 4/20 0.44
LMNA P02545 2/20 0.44
HEXA P06865 1/20 0.44
HEXB P07686 1/20 0.44
POLB P06746 1/20 0.44
PABPC1 P11940 1/20 0.44
XBP1 P17861 1/20 0.44
NFKB1 P19838 1/20 0.44
HTT P42858 1/20 0.44
SMARCA2 P51531 1/20 0.44
NFKB2 Q00653 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7712333 0.82 KDM4E (0.62) KMT2AMEN1KDM4EGAARECQL
SCHEMBL13495349 0.82 TDP1 (0.44) KMT2AMEN1KDM4EGAARECQL
SCHEMBL13495355 0.82 TDP1 (0.44) KMT2AMEN1KDM4EGAARECQL
SCHEMBL10040988 0.82 TDP1 (0.60) KMT2AMEN1KDM4EGAARECQL
SCHEMBL9041392 0.81 TOP1 (0.51) KMT2AMEN1KDM4EPRMT1TDP1
SCHEMBL13495346 0.77 PRMT1 (0.74) KMT2AMEN1KDM4EGAAPRMT1
SCHEMBL827965 0.76 MAPT (0.55) KMT2AMEN1KDM4EGAARECQL
SCHEMBL27927328 0.74 MAPT (0.55) KMT2AMEN1KDM4EGAARECQL
SCHEMBL7709655 0.74 TYMS (0.56) KMT2AMEN1KDM4EGAARECQL
SCHEMBL28678417 0.73 PARP1 (0.58) KMT2AMEN1KDM4EPRMT1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329377-B2 Imide compound and chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-11 US disclosed
US-8329377-B2 Imide compound and chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-11 US disclosed
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-02-04 US disclosed
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same IGF1R, CCNA1, MYC KMT2A 219/4885MEN1 98/4885KDM4E 1539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.