Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865632 | 0.83 | MEN1 (0.55) | DYRK1AIDO1KDM4EMEN1USP2 | |
| SCHEMBL864002 | 0.81 | MAPT (0.44) | DYRK1AIDO1KDM4EMEN1USP2 | |
| SCHEMBL863988 | 0.75 | MEN1 (0.56) | IDO1KDM4EMEN1USP2MAPT | |
| SCHEMBL865175 | 0.74 | MEN1 (0.53) | IDO1KDM4EMEN1USP2MAPT | |
| SCHEMBL864674 | 0.73 | MEN1 (0.53) | IDO1KDM4EMEN1USP2MAPT | |
| SCHEMBL864499 | 0.72 | MEN1 (0.66) | DYRK1AIDO1KDM4EMEN1USP2 | |
| SCHEMBL865835 | 0.72 | MEN1 (0.55) | IDO1KDM4EMEN1USP2MAPT | |
| SCHEMBL864436 | 0.72 | MEN1 (0.55) | IDO1KDM4EMEN1USP2MAPT | |
| SCHEMBL864562 | 0.72 | MEN1 (0.55) | IDO1KDM4EMEN1USP2MAPT | |
| SCHEMBL10250092 | 0.72 | MEN1 (0.57) | IDO1KDM4EMEN1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019208-A1 | FLAVIN DERIVATIVES | BIORELIX PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |