Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 14/20 | 0.72 |
| ▸ | CDK5R1 | Q15078 | 14/20 | 0.72 |
| ▸ | CCNA2 | P20248 | 12/20 | 0.72 |
| ▸ | CDK2 | P24941 | 12/20 | 0.72 |
| ▸ | CCNA1 | P78396 | 12/20 | 0.72 |
| ▸ | CDK1 | P06493 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.72 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.72 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.72 |
| ▸ | INSR | P06213 | 2/20 | 0.72 |
| ▸ | PRKACA | P17612 | 2/20 | 0.72 |
| ▸ | PRKACG | P22612 | 2/20 | 0.72 |
| ▸ | PRKACB | P22694 | 2/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.72 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.72 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.72 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497968 | 0.95 | CDK5 (0.73) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL14499679 | 0.93 | CDK5 (0.72) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL13497904 | 0.91 | CDK5 (0.67) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL14499686 | 0.90 | CDK5 (0.68) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL13497946 | 0.90 | CDK5 (0.68) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL14177997 | 0.84 | CDK5 (0.68) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL13498146 | 0.84 | CDK5 (0.87) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| Purvalanol B SCHEMBL27951 | 0.84 | CDK5 (1.00) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| Purvalanol B SCHEMBL6932922 | 0.84 | CDK5 (1.00) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL13497847 | 0.83 | CDK5 (0.86) | CDK5CDK5R1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048890-A1 | CONJUGATED SMALL MOLECULES | DISCOVERX CORPORATION | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048890-A1 | CONJUGATED SMALL MOLECULES | ERBB2, ALK, ACP1 | CDK5 803/4885CDK5R1 1525/4885CCNA2 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.