Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.60 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28702035 | 0.96 | CYP2D6 (0.93) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| SCHEMBL15184744 | 0.91 | CYP2D6 (0.83) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| SCHEMBL14720645 | 0.87 | SLC18A3 (0.83) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| SCHEMBL2965273 | 0.87 | SLC18A3 (0.81) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| SCHEMBL24163290 | 0.85 | SLC18A3 (0.79) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| SCHEMBL11121512 | 0.85 | SLC18A3 (1.00) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| SCHEMBL7888827 | 0.85 | SLC18A3 (1.00) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7879553 | 0.84 | SLC18A3 (0.96) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| SCHEMBL30563652 | 0.83 | SLC18A3 (0.96) | CYP2D6CYP2C19SLC18A3HPGDKMT2A | |
| Cyanide SCHEMBL27976792 | 0.81 | SLC18A3 (0.73) | CYP2D6CYP2C19SLC18A3HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014948-A1 | METHODS OF TREATMENT USING WNT INHIBITORS | THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-02-04 | — | — | WO | disclosed |