Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536425 | 0.94 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL3533283 | 0.94 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL13499174 | 0.91 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL3529422 | 0.91 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL3535088 | 0.91 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL3531643 | 0.88 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL3534848 | 0.86 | BDKRB1 (0.58) | BDKRB1 | |
| SCHEMBL3532823 | 0.85 | BDKRB1 (0.57) | BDKRB1 | |
| SCHEMBL3531090 | 0.85 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL3541815 | 0.85 | BDKRB1 (0.63) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662811-B2 | N-(((5R)-5-((1-methylethyl)amino)-5,6,7,8-tetrahydro-2-naphthalenyl)methyl)-2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-1,2,3,4-tetrahydro-2-pyrazinyl)acetamide; for treatment of pain and diseases, such as inflammation mediated diseases | AMGEN INC. (US) | 2010-02-16 | — | — | US | disclosed |