Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 2/20 | 0.83 |
| ▸ | CHEK1 | O14757 | 17/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500915 | 0.98 | CYBB (0.80) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500931 | 0.95 | CYBB (0.76) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500916 | 0.94 | CYBB (0.85) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500943 | 0.93 | CYBB (0.76) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500781 | 0.93 | CYBB (0.82) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500776 | 0.93 | CYBB (0.78) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500923 | 0.92 | CYBB (0.72) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500966 | 0.92 | CYBB (0.72) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500926 | 0.92 | CYBB (0.72) | CYBBCHEK1SLC2A1 | |
| SCHEMBL13500922 | 0.92 | CYBB (0.72) | CYBBCHEK1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662826-B2 | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same | SHIONOGI & CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |